Preparation of amines
Preparation of amines
Formula
RCN + 4[H] →[LiAlH₄] RCH₂NH₂
Real World
DuPont manufactures hexamethylenediamine (a key nylon-6,6 monomer) by reducing adiponitrile with hydrogen — an industrial-scale version of nitrile-to-amine reduction.
Exam Focus
Specify the reducing agent precisely: use LiAlH₄ in dry ether for nitrile reduction, not NaBH₄ which is too weak.
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